Stapled Antimesenteric Functional End-to-end Anastomosis (Kono-S) Versus Stapled Antimesenteric Isoperistaltic Side-to-side Anastomosis for the Postoperative Recurrence of Crohn's Disease: a Randomized Control Trial Study
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The postoperative recurrence of Crohn's diseases (CD) remains high. Stapled anti-mesenteric functional end-to-end anastomosis was safe for CD patients. Its impact on the postoperative recurrence of CD was unknown. Whether it is superior than the conventional anastomosis (stapled antimesenteric isoperistaltic side-to-side anastomosis) needs explored. The trial aims to compare the different impacts of the two antimesenteric anastomosis configurations on the anastomotic recurrence following bowel resection.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Maximum Age: 60
Healthy Volunteers: f
View:
• patients with Crohn's disease needing bowel resection and anastomosis;
• ileocolic anastomosis；
• written consent acquired
Locations
Other Locations
China
Department of General Surgery, Jinling hosptal,Medical School of Nanjing University
RECRUITING
Nanjing
Contact Information
Primary
ming duan, M.D.
duanming1206@126.com
+86-025-80860036
Time Frame
Start Date: 2022-12-08
Estimated Completion Date: 2029-12
Participants
Target number of participants: 236
Treatments
Experimental: Kono-S group
patients in this arm will receive stapled Kono-S anastomosis after bowel resection
Other: Side-to-side group
patients in this arm will receive stapled antimesenteric isoperistaltic side-to-side anastomosis after bowel resection
Related Therapeutic Areas
Sponsors
Leads: Jinling Hospital, China